• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.

Plan Your Next Event With a View at Panini's Cafe on the Waterfront in Beautiful Beaufort, SC

Waterfront View at Panini'sWhether you are planning a rehearsal dinner, family reunion, graduation celebration or a business luncheon, the location and atmosphere truly sets the mood for the occasion. If you are looking for a relaxed and Southern yet upscale and coastal ambiance for your get together, Panini's on the Waterfront is truly where you want to be; and where your guests will be talking about for years to come! It is our pleasure to make your event a special and memorable one; and we welcome you to stop in to see all that we have to offer for your special occasion!  Read More →

Beaufort Water Festival 2015

Beaufort Water FestivalThe Beaufort Water Festival is Beaufort South Carolina’s Premier Water and Air Event. Since 1956, The Beaufort Water Festival has brought residents and visitors from Beaufort, Charleston, Savannah, Hilton Head Island and parts beyond together in a two-week long celebration of the coastal Lowcountry. The Beaufort Water Festival is comprised of more then two dozen individual events including sporting events, aquatic events, arts & crafts, music and of course, the best of Lowcountry cuisine.  Read More →